InstallShield – ISSCH.EXE
Issch.exe is one of the InstallShield redistributable files. InstallShield is a very popular program used to install other programs. Due to the nature of this program, it could be used to install good programs or programs you don't really want. When things are working normally, Installshield should run, the program should be installed, then any temporary files should be removed. More info can be found at http://support.installshield.com/kb/view.asp?articleid=q104371.
If you see this file in your active tasks and you've just installed something, try rebooting. It's likely that will make it go away. If not, consider removing it using WinPatrol.
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Macrovision