Multiple Programs – POSTUPDATE.EXE
If you've just updated your Macromedia Flash or Shockwave player and you have a file called postupdate.exe in your c:\Windows\system32\Macromed\Shockwave 10, (number may vary) the file is most likely safe. Rebooting your system may get rid of it. You'll find more information and the latest versions of these players at http://www.adobe.com/shockwave/download/alternates/.
If you have a file called postupdate.exe in your c:\Program Files\Ad-Spider\update\ folder, you have Adware.AdSpider. AdSpider displays popup and embedded ads. It generally installs with free programs that are intentionally downloaded. You'll find more information at http://fileinfo.prevx.com/QQ436617083934-POST3774197/POSTUPDATE.EXE.html.
If you have the malicious instance of this file, we'd recommend removing this file using WinPatrol. First, kill it under Active Tasks then remove it from your Startup Programs. If running WinPatrol 8.x or later, right click the file then select "Delete file on Reboot". Finally, reboot your system.
Safe if not Adware